Hua Xie

Nov 5, 2024 | nature.com | Adam Kaminski |Hua Xie

AbstractWidely prescribed for Attention-Deficit/Hyperactivity Disorder (ADHD), stimulants (e.g., methylphenidate) have been studied for their chronic effects on the brain in prospective designs controlling dosage and adherence. While controlled approaches are essential, they do not approximate real-world stimulant exposure contexts where medication interruptions, dosage non-compliance, and polypharmacy are common. Brain changes in real-world conditions are largely unexplored.

Oct 7, 2024 | biorxiv.org | Hao Yue Zhu |Xiaoyu Tong |Nancy Carlisle |Hua Xie

AbstractBackground: Major depressive disorder (MDD) is a prevalent psychiatric disorder characterized by substantial clinical and neurobiological heterogeneity. Conventional studies that solely focus on clinical symptoms or neuroimaging metrics often fail to capture the intricate relationship between these modalities, limiting their ability to disentangle the complexity in MDD.

Aug 27, 2024 | nature.com | Hua Xie

AbstractThe ecological benefits and concerns surrounding fossil fuels had led to increased interest in bio-based rigid polyurethane foam (RPUF). Nonetheless, due to its flammability, it had limited application in various fields.

Jul 28, 2024 | nature.com | Hua Xie

AbstractThe concept of sustainable development has led to a growing research interest in bio-based flame-retardant polyurethane foams. These foams offer environmentally friendly, sustainable, and flame-retardant raw materials for the construction, automotive, and furniture industries. The 15 wt% soybean oil-based polyol rigid polyurethane foams (RPUF-S3A20B system) were modified with 20 wt% ammonium polyphosphate (APP) and homemade magnesium borate hydroxide (MgBO2(OH)).

May 24, 2023 | pubmed.ncbi.nlm.nih.gov | Xiaoyu Tong |Hua Xie |Wei Wu |Corey Keller

This is a preprint. It has not yet been peer reviewed by a journal. The National Library of Medicine is running a pilot to include preprints that result from research funded by NIH in PMC and PubMed. Display options Abstract Antidepressant medications yield unsatisfactory treatment outcomes in patients with major depressive disorder (MDD) with modest advantages over the placebo.