Hugo Botha

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Cortical microstructural abnormalities in dementia with Lewy bodies and their associations with Alzheimer’s disease copathologies - npj Parkinson's Disease

3 weeks ago | nature.com | Christopher Schwarz |Matthew L. Senjem |Prashanthi Vemuri |Leah Forsberg |David Jones |Hugo Botha | +7 more

AbstractDementia with Lewy bodies (DLB) frequently coexists with Alzheimer’s disease pathology, yet the pattern of cortical microstructural injury and its relationship with amyloid, tau, and cerebrovascular pathologies remains unclear.
DATScan in Mild Cognitive Impairment

Sep 18, 2023 | n.neurology.org | Farwa Ali |Hugo Botha

Several neurodegenerative diseases affect the midbrain dopaminergic system. A key component of disease pathogenesis is dysfunction of presynaptic dopamine neurotransmission by the dopamine transporter (DAT).

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