Huiqiao Chen

Sep 13, 2024 | biorxiv.org | Haoran Wu |Yuxi He |Huiqiao Chen |Weiyue Sun

AbstractObjective: We investigated the role of the RNA-binding protein G3BP1 in regulating endothelial permeability. Approach and Results: We examined the effects of loss of G3bp1 in conditional knockout mice and primary human HUVEC cells. We analyzed endothelial barrier integrity and permeability, focusing on AJ and TJ expression, under both normal and LPS-induced inflammatory conditions.