Humza Hemani

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SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors | Nature Communications

Oct 23, 2023 | nature.com | Jiangyuan Li |Daichao Wu |Humza Hemani |Rui Yin |Christopher Dunn |Richard Willis | +7 more

AbstractThe resolution of SARS-CoV-2 replication hinges on cell-mediated immunity, wherein CD8+ T cells play a vital role. Nonetheless, the characterization of the specificity and TCR composition of CD8+ T cells targeting non-spike protein of SARS-CoV-2 before and after infection remains incomplete.

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