Christopher Dunn

2 weeks ago | biorxiv.org | Oscar Rodriguez |Oscar Rodríguez |Óscar Rodríguez |Xiang Qiu |Kaitlyn T Shields |Christopher Dunn

AbstractThe peripheral antibody repertoire is shaped by inherited genetic variation and selection during B cell development. However, how the repertoire changes across developmental stages and the relative impact of genetics and selection in establishing the antibody repertoire remain largely unknown.

Oct 23, 2023 | nature.com | Jiangyuan Li |Daichao Wu |Humza Hemani |Rui Yin |Christopher Dunn |Richard Willis | +7 more

AbstractThe resolution of SARS-CoV-2 replication hinges on cell-mediated immunity, wherein CD8+ T cells play a vital role. Nonetheless, the characterization of the specificity and TCR composition of CD8+ T cells targeting non-spike protein of SARS-CoV-2 before and after infection remains incomplete.