Ian K. Blaby

Nov 4, 2024 | nature.com | Dengxun Lai |Xavier Mayali |Steffen Buessecker |Ariane Briegel |Tanja Woyke |Emiley A Eloe-Fadrosh | +13 more

AbstractFew aerobic hyperthermophilic microorganisms degrade polysaccharides. Here, we describe the genome-enabled enrichment and optical tweezer-based isolation of an aerobic polysaccharide-degrading hyperthermophile, Fervidibacter sacchari, previously ascribed to candidate phylum Fervidibacteria. F.

Oct 10, 2024 | jbc.org | Audrey Fahey |Michael Regulski |Ian K. Blaby

KeywordsironchloroplastAT3G03890HOZAT1G51560HOZ2AAT3G21140HOZ2BGluTRBPIntroductionIron is an essential micronutrient that functions in a wide range of biological processes. To control the chemical properties of the iron atom and catalyze a specific activity, multiple proteins and complexes bind a prosthetic group where iron is bound to a protoporphyrin ring (i.e., heme).

Jul 2, 2024 | analyticalsciencejournals.onlinelibrary.wiley.com | Patrick A. Sanford |Ian K. Blaby |Yasuo Yoshikuni |Benjamin M. Woolston

Acetogenic Clostridia are anaerobic bacteria of increasing academic and industrial interest thanks to their unique ability to metabolize single carbon substrates at high energetic efficiency, giving them significant potential in the development of the circular bioeconomy and to combat climate change (Bar-Even et al., 2012; Schuchmann & Müller, 2014).

Apr 12, 2024 | nature.com | Nicolas Grosjean |Estella F. Yee |Kriti Chopra |Sandeep Biswas |Jan-Fang Cheng |Agnidipta Ghosh | +6 more

AbstractHeme has a critical role in the chemical framework of the cell as an essential protein cofactor and signaling molecule that controls diverse processes and molecular interactions. Using a phylogenomics-based approach and complementary structural techniques, we identify a family of dimeric hemoproteins comprising a domain of unknown function DUF2470.

Jul 27, 2023 | nature.com | Sarah P Esser |Janina Rahlff |Franziska Wimmer |Janey Lee |Panagiotis S. Adam |Mart Krupovic | +8 more

Author notes Janina Rahlff Present address: Centre for Ecology and Evolution in Microbial Model Systems (EEMiS), Department of Biology and Environmental Science, Linnaeus University, Kalmar, Sweden Weishu Zhao Present address: Shanghai Jiao Tong University, School of Life Sciences and Biotechnology, International Center for Deep Life Investigation (IC-DLI), Shanghai Jiao Tong University, Shanghai, China Katrin Schwank Present address: University of Regensburg, Biochemistry III, Regensburg,...