Ignacio Melero Bermejo

Nov 8, 2023 | nature.com | Joshua A. Bull |Martin Sergeant |Rachel Etherington |Fadi Issa |Ignacio Melero Bermejo |Simon J. McGowan | +11 more

AbstractSingle cell spatial interrogation of the immune-structural interactions in COVID −19 lungs is challenging, mainly because of the marked cellular infiltrate and architecturally distorted microstructure. To address this, we develop a suite of mathematical tools to search for statistically significant co-locations amongst immune and structural cells identified using 37-plex imaging mass cytometry.