Igor Delvendahl

Sep 20, 2024 | cell.com | Michael Lin |Yukun Hao |Sungmoo Lee |Richard Roth |Silvia Natale |Laura Gomez | +13 more

1Department of Bioengineering, Stanford University, Stanford, CA 94305, USA 2Department of Neurobiology, Stanford University, Stanford, CA 94305, USA 3Department of Neurosurgery, Stanford University, Stanford, CA 94305, USA 4Department of Molecular & Cellular Physiology, Stanford University, Stanford, CA 94305, USA 5Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA 94720, USA 6Department of Physics, University of...

Feb 14, 2024 | nature.com | Marian Hruska-Plochan |Vera I. Wiersma |Katharina M. Betz |Elena Tantardini |Florent Laferrière |Igor Delvendahl | +11 more

AbstractHuman cellular models of neurodegeneration require reproducibility and longevity, which is necessary for simulating age-dependent diseases. Such systems are particularly needed for TDP-43 proteinopathies1, which involve human-specific mechanisms2,3,4,5 that cannot be directly studied in animal models.