Irene N. Nkumama

May 23, 2024 | cell.com | Irene N. Nkumama |Rodney Ogwang |Dennis Odera |Fauzia Musasia

Highlights•Used a human malaria infection study to investigate functional correlates of immunity•IgG Fc-dependent mechanisms are correlated with acquired immunity, but GIA is not•The breadth of IgG Fc-effector function is associated with protective immunitySummaryMalaria is a life-threatening disease of global health importance, particularly in sub-Saharan Africa.