Ivone Jakasa

Jul 30, 2024 | onlinelibrary.wiley.com | Lise Gether |Sanja Kezic |Ivone Jakasa |Julie Forman

CONFLICT OF INTEREST STATEMENT During this project, L. Gether worked as an industrial PhD student partly funded by LEO Pharma. L.

Jan 22, 2024 | onlinelibrary.wiley.com | Monica Young |Sanja Kezic |Amsterdam UMC |Ivone Jakasa

1 INTRODUCTION Natural moisturising factor (NMF) in human skin is one of the key components in maintaining skin barrier homeostasis. NMF mainly consists of free amino acids and their derivatives that act as humectants in the stratum corneum (SC) by attracting water molecules and hydrating the skin.1 NMF components including urocanic acid (UCA) and pyrrolidone carboxylic acid (PCA) are products from the hydrolysis of the SC structural protein, filaggrin.

Feb 19, 2023 | bmjopen.bmj.com | Iben Frier Ruge |Anne-Sofie Halling |Blaine Gabriel Fritz |Ivone Jakasa

Skin measurementsAll tape strips, skin swabs and skin biopsies are collected from lesional and non-lesional areas of the skin in patients with AD and at a corresponding area from the controls. Samples from lesional skin are collected in the following priority (eg, if no lesional skin in elbow flexure, move to next skin site): elbow flexure, volar forearm, knee flexure, thigh, abdomen, flanks, back, buttocks and neck.