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2 weeks ago | 00090-7/abstract?rss=yes&sz=64)
thelancet.com | Amsterdam UMC |Elizabeth Winter |Einthoven Laboratory |Natasha M. Appelman-Dijkstra
Get full text accessLog in, subscribe or purchase for full access. References1. Paccou, J ∙ Compston, JEBone health in adults with obesity before and after interventions to promote weight lossLancet Diabetes Endocrinol. 2024; 12:748-7602. Muskiet, MHA ∙ Tonneijck, L ∙ Smits, MM ∙ et al. GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetesNat Rev Nephrol. 2017; 13:605-6283.
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2 months ago | 
bmcpublichealth.biomedcentral.com | den Elzen |Amsterdam UMC
Based on the interviews, six dimensions could be identified that participants use to define vitality (Table 2). Participants described physical, cognitive and social capacities as dimensions of vitality. Next to these capacities, the participants described the importance of drivers in life for vitality. These drivers in life also encompassed three dimensions: independency, autonomy and meaning in life.
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2 months ago | 
bmcpublichealth.biomedcentral.com | S. Coosje |Healthy Lifestyles |Amsterdam UMC
ResultsThe CLD as presented in Fig. 3 shows the system that shapes a healthy and sustainable food environment in healthcare institutions, formed by 30 factors, connections and mechanisms that influence the system. The arrows symbolize the connections between factors. An arrow with a plus symbol indicates that the relationship between the factors is positive (if the variable increases or decreases, the connected variable also increases or decreases correspondingly).
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2 months ago | 
bmcmedicine.biomedcentral.com | Van Nassau |Amsterdam UMC |Vrije Universiteit Amsterdam
The interviews were conducted between May and November 2022. In total, 29 interviews were conducted with 30 participants (one duo interview), of which 12 interviews in hospital one, 10 interviews in hospital two, and 7 in hospital three. A total of 18 interviews were conducted online via Microsoft Teams or by telephone and 11 interviews in person in the hospital. The interviews were audio-recorded and lasted between 24 and 70 min.
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Jan 11, 2025 | 00523-6/fulltext&sz=64)
thelancet.com | Amsterdam UMC |Rick H Hulskes |Robert Weenink |Location the
KeywordsSystematic reviewMeta-analysisGoal-directed haemodynamic therapySurgical site infectionWound infectionSurgeryAnaesthesiologyEvidence before this studySurgical site infections (SSI) and other postoperative complications pose a significant challenge, particularly with the growing threat of antimicrobial resistance. Goal-directed haemodynamic therapy (GDHT) is a highly investigated intervention to prevent several postoperative complications, including SSI.
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Jan 6, 2025 | 
onlinelibrary.wiley.com | Maarten G. Poirot |Amsterdam UMC |Physics Amsterdam UMC |Amsterdam Neuroscience
FreeSurfer-derived cortical thickness and surface area measures showed no predictive value for pharmacotherapeutic treatment response in major depressive disorder in the current sample of the population at large. Classification performance was not dependent on machine learning pipeline configuration, that is, cortical data representation, the inclusion of clinical data, the machine learning method used, or the cross-validation scheme used.
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Dec 10, 2024 | 
onlinelibrary.wiley.com | Tamara Verkerk |Landsteiner Laboratory |Amsterdam UMC |Jasper Sanders
1 Introduction To establish an effective antitumor response, immune cell receptors work synergistically to mediate and fine-tune cellular responses. Functional interaction between receptors and their ligands is necessary to activate the right pro-inflammatory immune cells or inhibit suppressive cells for a specific, yet balanced immune response.
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Dec 10, 2024 | 
academic.oup.com | Amsterdam UMC |Stichting HIV Monitoring |van der Valk
People with HIV (PWH) experience a higher burden of ageing-associated comorbidities, the underlying mechanisms of which remain to be fully elucidated. We aimed to identify profiles based on immune, inflammatory, and ageing biomarkers in blood from PWH and controls, and explore their association with total comorbidities over time.
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Dec 6, 2024 | 
academic.oup.com | Amsterdam UMC |Erik S. G |Vrije Universiteit Amsterdam |Cheyenne Y Y
Inflammation is an important driver of disease in the context of atherosclerosis, and several landmark trials have shown that targeting inflammatory pathways can reduce cardiovascular event rates. However, the high cost and potentially serious adverse effects of anti-inflammatory therapies necessitate more precise patient selection.
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Dec 6, 2024 | 
academic.oup.com | Amsterdam UMC
The COVID-19 pandemic may have disproportionally impacted vulnerable groups such as people who inject drugs (PWID) through reduced healthcare services as well as social changes from pandemic mitigation measures. Understanding how the COVID-19 pandemic and associated mitigation strategies subsequently changed the trajectory of hepatitis C virus (HCV) and HIV transmission is critical to estimating disease burdens, identifying outbreak risk, and developing informed intervention strategies.
