Jack Freestone

1 month ago | medicalxpress.com | Jack Freestone |Krista J. Siefried

Gamma hydroxybutyrate—better known as GHB—is an increasingly popular illegal drug being used recreationally in Australia. While it can create feelings of euphoria, disinhibition and increased libido, GHB carries serious risks. The difference between a recreational dose and an overdose of GHB—usually taken as a liquid—can be less than 0.5ml. What is GHB? GHB (also sometimes called "G," "juice," "Gina" or "fantasy") has gained attention globally due to associated harms.

1 month ago | theconversation.com | Jack Freestone |Krista J. Siefried

Gamma hydroxybutyrate – better known as GHB – is an increasingly popular illegal drug being used recreationally in Australia. While it can create feelings of euphoria, disinhibition and increased libido, GHB carries serious risks. The difference between a recreational dose and an overdose of GHB – usually taken as a liquid – can be less than 0.5ml. What is GHB? GHB (also sometimes called “G”, “juice”, “Gina” or “fantasy”) has gained attention globally due to associated harms.

2 months ago | dx.doi.org | Jack Freestone |Lukas Käll |William Noble |Uri Keich

Oct 20, 2024 | biorxiv.org | Jack Freestone |Michael Riffle |Michael J MacCoss |William Noble

AbstractA pressing statistical challenge in the field of mass spectrometry proteomics is how to assess whether a given software tool provides accurate error control. Each software tool for searching such data uses its own internally implemented methodology for reporting and controlling the error. Many of these software tools are closed source, with incompletely documented methodology, and the strategies for validating the error are inconsistent across tools.

Jun 4, 2024 | biorxiv.org | Jack Freestone |Michael J MacCoss |William Noble |Michael Riffle

AbstractA pressing statistical challenge in the field of mass spectrometry proteomics is how to assess whether a given software tool provides accurate error control. Each software tool for searching such data uses its own internally implemented methodology for reporting and controlling the error. Many of these software tools are closed source, with incompletely documented methodology, and the strategies for validating the error are inconsistent across tools.