Jacob Stanley

Nov 23, 2024 | biorxiv.org | Jacob Stanley |Hope A Townsend |Rutendo F. Sigauke |Mary Allen

AbstractTranscription by RNA polymerases is an exquisitely regulated step of the central dogma. Transcription is the primary determinant of cell-state, and most cellular perturbations impact transcription by altering polymerase activity. Thus, detecting changes in polymerase activity yields insight into most cellular processes. Nascent run-on sequencing provides a direct readout of polymerase activity, but no tools exist to model this activity at genes.

Jun 12, 2023 | cell.com | Jacob Stanley

Sep 10, 2018 | comicsbulletin.com | Jacob Stanley

Aug 29, 2018 | comicsbulletin.com | Jacob Stanley