Jakob Usemann

Nov 23, 2024 | nature.com | Ruth Steinberg |Jakob Usemann |Alexander Moeller |Sylvain Blanchon |Urs Frey |Philipp Latzin | +2 more

AbstractRespiratory tract infections (RTIs) drive lung function decline in children with cystic fibrosis (CF). While the respiratory microbiota is clearly associated with RTI pathogenesis in infants without CF, data on infants with CF is scarce. We compared nasal microbiota development between infants with CF and controls and assessed associations between early-life nasal microbiota, RTIs, and antibiotic treatment in infants with CF.

Jul 10, 2024 | onlinelibrary.wiley.com | Jakob Usemann |Rebeca Mozun |Claudia E. Kuehni |Kees de Hoogh

1 BACKGROUND Traffic-related air pollutants are known to have detrimental effects on respiratory morbidity and lung functional development.1-5 There is growing awareness that exposure to air pollution especially in early-life, has an impact on a child's respiratory health, with potential long-term effects on lung function trajectories throughout life.6, 7 The association between air pollution exposure after birth and later lung function is reported consistently.2, 3, 8, 9 Several studies have...