Urs Frey

Nov 23, 2024 | nature.com | Ruth Steinberg |Jakob Usemann |Alexander Moeller |Sylvain Blanchon |Urs Frey |Philipp Latzin | +2 more

AbstractRespiratory tract infections (RTIs) drive lung function decline in children with cystic fibrosis (CF). While the respiratory microbiota is clearly associated with RTI pathogenesis in infants without CF, data on infants with CF is scarce. We compared nasal microbiota development between infants with CF and controls and assessed associations between early-life nasal microbiota, RTIs, and antibiotic treatment in infants with CF.

Jul 19, 2024 | onlinelibrary.wiley.com | Florian Wyler |Thuvarakha Manogaran |Nathalie Monney |Yasmin Ahmed Salem |Ruth L. Steinberg |Noemi Künstle | +7 more

May 28, 2024 | nature.com | Urs Frey

AbstractPreterm infants are susceptible to oxidative stress and prone to respiratory diseases. Autophagy is an important defense mechanism against oxidative-stress-induced cell damage and involved in lung development and respiratory morbidity. We hypothesized that autophagy marker levels differ between preterm and term infants.