James Carmichael

Mar 22, 2024 | science.org | Johannes Lohmann |Hassan Alnatah |Ilke Uguz |Céline Moison |Julie Schmitt |Simon L. Girard | +12 more

Research Article CANCER Céline Moison https://orcid.org/0009-0008-5381-3546 [email protected], Deanne Gracias, [...] , Julie Schmitt, Simon Girard, [...] , Jean-François Spinella, Simon Fortier https://orcid.org/0000-0002-3492-0759, Isabel Boivin https://orcid.org/0000-0002-1216-3240, Rodrigo Mendoza-Sanchez https://orcid.org/0000-0002-6143-6620, Bounkham Thavonekham, [...] , Tara MacRae https://orcid.org/0000-0003-0938-4496, Nadine Mayotte https://orcid.org/0000-0003-1739-3106, Eric...

Oct 1, 2023 | biorxiv.org | Richard Boyce |Hyun Yong |James Carmichael |Mark Brandon

AbstractThe involvement of rapid-eye-movement sleep (REMs) in spatial memory formation was recently demonstrated, although how neural activity during REMs influences newly-formed place field stability remains unclear. Here, we combined large-scale single-unit recordings of mouse hippocampal CA1 with an established optogenetic approach enabling REMs-selective inhibition of medial septum GABAergic neurons (MSGABA), resulting in spatial memory deficits when applied post-learning.