Mark Brandon

Nov 22, 2024 | cell.com | J. Lee |Alexandra T. Keinath |Erica Cianfarano |Mark Brandon

KeywordshippocampusCA1cognitive mappingremappingrepresentational similaritycalcium imagingspatial cognitionnavigationcomputational modelingplace cellsGet full text accessLog in, subscribe or purchase for full access. References1. O’Keefe, J. ∙ Nadel, L. The Hippocampus as a Cognitive Map2. Nieh, E.H. ∙ Schottdorf, M. ∙ Freeman, N.W. ... Geometry of abstract learned knowledge in the hippocampusNature. 2021; 595:80-843. Lee, J.S. ∙ Briguglio, J.J. ∙ Cohen, J.D. ...

Oct 15, 2024 | mallemaroking.org | Mark Brandon

I love looking at satellite images of the Antarctic and picking out the icebergs. In the last few years we have had great stories about the giant icebergs A68 in 2020, A76 in 2022 and most recently A23a currently in the Southern Scotia Sea. At the moment there are two of very large icebergs at the southern end of Antarctic Sound. Here is a map to orientate yourself and show where they are. There is a lot in the image above. As well as the Antarctic Peninsula there are clouds, sea ice, and icebergs.

Aug 26, 2024 | biorxiv.org | Saishree Badrinarayanan |Rosa Sundar-Maccagno |Mark Brandon |Marie Oulé

AbstractHead-direction (HD) cells are found across several regions in the brain, including the anterodorsal thalamic nucleus (ADN), the subicular complex, and the medial entorhinal cortex (MEC). A fundamental role of head direction cells is to provide input to MEC grid cells, which are thought to translate information about head direction into a metric code for spatial location.

Aug 19, 2024 | cell.com | Jennifer Robinson |Johnson Ying |Michael E. Hasselmo |Mark Brandon

Highlights•Medial septum (MS)-GABAergic inhibition reduces theta rhythms•MS-GABAergic inhibition disrupts grid cell spatial periodicity and theta phase precession•Theta rhythm is restored immediately after MS-GABAergic inhibition•Grid cell spatial coding takes longer (60 s) to recover from MS-GABAergic inhibitionSummaryThe hippocampus and medial entorhinal cortex (MEC) form a cognitive map that facilitates spatial navigation.

Nov 10, 2023 | biorxiv.org | Jennifer Robinson |Johnson Ying |Michael E. Hasselmo |Mark Brandon

AbstractThe hippocampus and medial entorhinal cortex (MEC) form a cognitive map that facilitates spatial navigation. As part of this map, MEC grid cells fire in a repeating hexagonal pattern across an environment. This grid pattern relies on inputs from the medial septum (MS). The MS, and specifically its GABAergic neurons, are essential for theta rhythm oscillations in the entorhinal-hippocampal network, however, it is unknown if this subpopulation is also essential for grid cell function.