James Chapman

Jan 2, 2024 | nature.com | Stella G. Victorelli |James Chapman |Joel Riley |Diana Jurk |Lilian Sales Gomez |Joshua N Farr | +11 more

Correction to: Nature https://doi.org/10.1038/s41586-023-06621-4 Published online 11 October 2023In the version of this article initially published, US NIH grants R33AG61456-4 and R01AG064165 were missing from the Acknowledgements section and have now been inserted in the HTML and PDF versions of the article.

Oct 11, 2023 | nature.com | Stella G. Victorelli |James Chapman |Joel Riley |Diana Jurk |Lilian Sales Gomez |Joshua N Farr | +11 more

AbstractSenescent cells drive age-related tissue dysfunction partially through the induction of a chronic senescence-associated secretory phenotype (SASP)1. Mitochondria are major regulators of the SASP; however, the underlying mechanisms have not been elucidated2. Mitochondria are often essential for apoptosis, a cell fate distinct from cellular senescence. During apoptosis, widespread mitochondrial outer membrane permeabilization (MOMP) commits a cell to die3.

Sep 11, 2023 | datacamp.com | James Chapman

James ChapmanAnalytics & Data Science Curriculum Manager at DataCampGet Started With AI Today!Learn how to use ChatGPT. Discover best practices for writing prompts and explore common business use cases for the powerful AI tool. Uncover AI's challenges and societal implications in this theoretical course. Discover machine learning, deep learning, NLP, generative models & more. Discover how to extract business value from AI.