James Curtain

Aug 30, 2024 | jamanetwork.com | Samantha Anderer |James Curtain |Marc A. Pfeffer |Eugene Braunwald

Contemporary Post-MI Treatments Reduce Risk of Sudden Death Rates of Sudden Death After Myocardial Infarction—VALIANT and PARADISE-MI Trials James P. Curtain, MB, BS; Marc A. Pfeffer, PhD; Eugene Braunwald, MD; Brian L. Claggett, PhD; Christopher B. Granger, MD; Lars Køber, MD, DSci; Eldrin F. Lewis, MD, MPH; Aldo P. Maggioni, MD; Doug L. Mann, MD; Jean L. Rouleau, MD; Scott D. Solomon, MD; Philippe Gabriel Steg, MD; Peter V. Finn, MD; Alberto Fernandez, MD; Karola S.

Aug 8, 2024 | jamanetwork.com | James Curtain |Marc A. Pfeffer |Brian Claggett |Christopher B Granger

Key PointsQuestion  Has the sudden death rate after myocardial infarction and the characteristics of people dying suddenly changed over time?

May 15, 2023 | heart.bmj.com | James Curtain |John McMurray |Roy S Gardner |Mark C. Petrie

DiscussionThe main results of this meta-analysis support the use of IHM in patients with symptomatic HF (irrespective of EF), demonstrating a 26% reduction in the risk of total worsening HF events, including hospital admission. This is the first meta-analysis to include total HF events from all IHM randomised trials, including LAPTOP-HF and the recently reported GUIDE-HF. We also report for the first time meta-analyses of the effectiveness of IHM-guided care in patients with HFrEF and HFpEF.