James M. Shine

Oct 16, 2024 | nature.com | Justine Y. Hansen |Simone Cauzzo |James M. Shine

AbstractThe brainstem is a fundamental component of the central nervous system, yet it is typically excluded from in vivo human brain mapping efforts, precluding a complete understanding of how the brainstem influences cortical function. In this study, we used high-resolution 7-Tesla functional magnetic resonance imaging to derive a functional connectome encompassing cortex and 58 brainstem nuclei spanning the midbrain, pons and medulla.

Nov 8, 2023 | nature.com | Emily Finn |James M. Shine

AbstractFunctional magnetic resonance imaging (fMRI) enables non-invasive access to the awake, behaving human brain. By tracking whole-brain signals across a diverse range of cognitive and behavioural states or mapping differences associated with specific traits or clinical conditions, fMRI has advanced our understanding of brain function and its links to both normal and atypical behaviour.

Jun 26, 2023 | movementdisorders.onlinelibrary.wiley.com | Michiel F. Dirkx |Movement Disorders |James M. Shine |Rick C. Helmich

Experimental Design and Behavioral Parameters We focused on cerebral between-network connectivity in two separate contexts: (1) periods of cognitive load interchanged with rest and (2) resting state. First, we focused on cerebral connectivity during periods of cognitive load for which we used a block design (5 × 1 minutes rest interchanged with 5 × 1 minutes performing mental arithmetic).