Articles

  • Mar 18, 2024 | cfp.ca | Jennifer Young |Erin Lee |Adrienne Lindblad |Jamie Falk

    Clinical questionAre orexin antagonists safe and effective for treatment of primary insomnia? Bottom lineOrexin antagonists help people fall asleep about 9 minutes faster and increase total sleep time by about 19 minutes versus placebo over the course of 1 to 3 months. About 8% of those taking orexin antagonists will experience next-day somnolence compared with 2% taking placebo. EvidenceSeven systematic reviews of RCTs were found1-7; we report mainly on the most recent and comprehensive review.

  • Jun 14, 2023 | cfp.ca | Samantha Moe |Michael R Kolber |Jamie Falk

    Research ArticleTools for Practice Canadian Family Physician 69 (6) 406; DOI: https://doi.org/10.46747/cfp.6906406 Clinical questionCompared with self-monitoring blood glucose (SMBG), does continuous glucose monitoring improve clinical outcomes or hemoglobin A1c (HbA1c) levels for adults with diabetes taking insulin?

  • May 12, 2023 | cfp.ca | Jamie Falk |Allison Paige |Nicolas Dugré |G. Michael Allan

    Research ArticleTools for Practice Canadian Family Physician 69 (5) 337; DOI: https://doi.org/10.46747/cfp.6905337 Clinical questionWhat are the effects of statins on muscles? Bottom lineStatins increase the risk of muscle symptoms (pain, cramps, weakness) in the first year of use, from 14.0% (placebo) to 14.8%, but are similar to placebo after 1 year.

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