Jan Vesper

Dec 5, 2024 | biorxiv.org | Lucie Winkler |Markus Butz |Abhinav Sharma |Jan Vesper

AbstractThe role of beta band activity in cortico-basal ganglia interactions during motor control has been studied extensively in resting-state and for simple movements, such as button pressing. However, little is known about how beta oscillations change and interact in more complex situations involving rapid changes of movement in various contexts.

Nov 11, 2024 | biorxiv.org | Alexandra Steina |Sarah Sure |Markus Butz |Jan Vesper

AbstractBackgroundEssential tremor is hypothesized to emerge from synchronized oscillatory activity within the cerebello-thalamo-cortical circuit. However, this hypothesis has not yet been tested using local field potentials directly recorded from the thalamus alongside signals from both the cortex and cerebellum, leaving a gap in the understanding of essential tremor. ObjectivesTo clarify the importance of cerebello-thalamo-cortical oscillatory coupling for essential tremor.

Aug 21, 2024 | biorxiv.org | Markus Butz |Abhinav Sharma |Jan Vesper |Lucie Winkler

AbstractThe role of beta band activity in cortico-basal ganglia interactions during motor control has been studied extensively in resting-state and for simple movements, such as button pressing. However, little is known about how beta oscillations change and interact in more complex situations involving rapid changes of movement in various contexts.

Feb 21, 2024 | movementdisorders.onlinelibrary.wiley.com | Alexandra Steina |Markus Butz |Jan Vesper |Sarah Sure

Essential tremor (ET) is the most common movement disorder with a global prevalence of 0.32% across all ages.1 ET patients suffer primarily from isolated upper limb intention tremor and postural tremor.2-4 The underlying pathophysiology is only partially understood, but abnormalities in the cerebello-thalamo-cortical circuit seem to play a key role in the generation of tremor.4-7 Deep brain stimulation (DBS) of the ventral intermediate nucleus of the thalamus (VIM) is a standard therapy to...