Janet Berrington

Aug 24, 2024 | nature.com | Janet Berrington

Meta-analysis of probiotic administration to very preterm or very low birthweight (VP/VLBW) infants shows reduced risk of necrotising enterocolitis (NEC). Separately reported outcomes for extremely preterm infants (<28 weeks) or extremely low birth weight infants (<1000 g) (EP/ELBW) are lacking meaning some clinicians do not administer probiotics to EP/ELBW infants despite their high risk of NEC.

Jun 12, 2024 | thelancet.com | John Lowe |Janet Berrington |David Gillespie

We thank Thomas and colleagues for their comments. The AZTEC study used prophylactic azithromycin aiming to improve survival without development of chronic lung disease of prematurity. The primary outcome was chosen after significant consideration, including ability to measure it in a large multicentre RCT1Lowe J Gillespie D Aboklaish A et al. Azithromycin therapy for prevention of chronic lung disease of prematurity (AZTEC): a multicentre, double-blind, randomised, placebo-controlled trial.