Jason Powell

Jun 11, 2024 | nature.com | David Ross |Jason Powell

AbstractAcute myeloid leukaemia (AML) is a highly aggressive and devastating malignancy of the bone marrow and blood. For decades, intensive chemotherapy has been the frontline treatment for AML but has yielded only poor patient outcomes as exemplified by a 5-year survival rate of < 30%, even in younger adults. As knowledge of the molecular underpinnings of AML has advanced, so too has the development new strategies with potential to improve the treatment of AML patients.

Apr 26, 2024 | link.springer.com | Jason Powell

AbstractIn this chapter, it is important to interrogate the role of the body so that one can move away from the modernist biomedical approach, which locates the body within the naturalistic framework. The postmodern perspective adds a richness to the literature by examining embodiment and the corporeality of the body in all its social guises.

Sep 15, 2023 | thorax.bmj.com | Jason Powell |Steven Powell |Michael Mather |Lauren Beck

Tracheostomy in children is associated with neutrophilic airway inflammation Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Feb 20, 2023 | thorax.bmj.com | Jason Powell |Steven Powell |Michael Mather |Lauren Beck

Long-term tracheostomy cohortWe aimed to evaluate the airway effects of tracheostomy further in a larger cohort of long-term tracheostomised patients. Tracheal aspirates demonstrated a distinct proteome compared with control aspirates (figure 4A,B). A large proportion of the significantly more abundant proteins identified in long-term tracheostomised patients compared with controls related to neutrophil degranulation (figure 4C).