Jay Rughani

Mar 26, 2024 | a16z.com | Kristina Shen |Zeya Yang |Jay Rughani |Ali Yahya

An enduring promise of new technologies is to find ways to increase human productivity. Software and robotics, for example, have always presented immense potential to automate repetitive mundane tasks that humans perform, freeing them up to do more valuable work. In the last few decades, we’ve made meaningful progress toward this goal, and the first generation of robotic process automation created some massive companies, such as UiPath. Yet, we never made it past the most simple tasks.

Dec 13, 2023 | a16z.com | Daisy Wolf |Adela Tomsejova |Jay Rughani |Vijay Pande

Over the past half century, Wall Street was completely revolutionized by computers. Not so long ago, human brokers on the stock exchange floor haggled to buy and sell every stock, writing their agreements on pieces of paper. But in 1971, the NASDAQ, the world’s first electronic stock exchange, was introduced. Electronic trading platforms followed in the 1980s, and the rise of the internet in the 1990s brought online brokerages like E*TRADE.

Dec 8, 2023 | a16z.com | Jorge Conde |Kris Tatiossian |Jay Rughani |Olivia Webb

Originally discovered in bacteria, CRISPR quickly became the workhorse gene-editing system underlying the next generation of programmable medicines. Today’s landmark approval by the US Food and Drug Administration of Vertex Pharmaceuticals’ and CRISPR Therapeutics’ Casgevy, the world’s first CRISPR-based treatment, marks a groundbreaking shift in how we tackle intractable diseases.

Nov 14, 2023 | a16z.com | Daisy Wolf |Julie Yoo |Jay Rughani |Vijay Pande

The internet and friendsYou’ve most likely had an experience like this:One day, you wake up with a hint of a headache and a sniffle. You sneeze. What do you do next? You Google it. You eventually land on WebMD. Was that sneeze a common cold or a bout of seasonal allergies? Or are you in fact dying from a rare form of nasal cancer? You determine you should see an allergist. But which one? How do you find a good one? Does your health plan require a referral? How much is this going to cost you?

Oct 13, 2023 | a16z.com | Sarah Wang |Jay Rughani |Julie Yoo |David Haber

Taking a company from idea to household name is always difficult. But the past few years presented challenges that caught even the most-seasoned CEOs off guard. After all, there’s not much in the way of a playbook for things like a pandemic, major swings in the global economy, and significant shifts in the employer-employee dynamic.