Jeffrey Golden

Jul 7, 2023 | cell.com | David Meredith |Keith L. Ligon |Jeffrey Golden

Highlights•We established the Cryosection Histopathology Assessment and Review Machine (CHARM)•CHARM predicted IDH mutation and 2021 WHO classification of glioma using cryosections•CHARM provided quantitative evidence supporting the reclassification of astrocytoma•CHARM facilitated real-time cryosection diagnoses and can be extended to other cancersContext and significanceReal-time pathology diagnosis of tissue samples is crucial for the optimal treatment of brain cancers.