Jeffrey Letourneau

Jan 8, 2025 | nature.com | Bingsen Zhang |Jeffrey Letourneau |Yousi Fu |Douglas V. Guzior |Robert Quinn |Chun-Jun Guo | +3 more

AbstractMetabolites derived from the intestinal microbiota, including bile acids (BA), extensively modulate vertebrate physiology, including development1, metabolism2,3,4, immune responses5,6,7 and cognitive function8. However, to what extent host responses balance the physiological effects of microbiota-derived metabolites remains unclear9,10.

Apr 28, 2024 | biorxiv.org | Jeffrey Letourneau |Veronica Carrion |Sharon Jiang |Olivia Osborne

AbstractPhysical particles can serve as critical abiotic factors that structure the ecology of microbial communities. For non-human vertebrate gut microbiomes, fecal particle size (FPS) has been known to be shaped by chewing efficiency and diet. However, little is known about what drives FPS in the human gut. Here, we analyzed FPS by laser diffraction across a total of 76 individuals and found FPS to be strongly individualized.