Jeffrey Winters

1 month ago | nature.com | Jacob J. Orme |Robert McWilliams |Robert Mcwilliams |Matthew Block |Aaron Mansfield |Svetomir N. Markovic | +3 more

AbstractImmune checkpoint inhibitors (ICI) are effective for advanced melanoma. However, most develop ICI resistance. Tumor-derived soluble PD-L1 (sPD-L1) and other immunosuppressive factors drive resistance. We hypothesized that therapeutic plasma exchange (TPE) may remove sPD-L1 from circulation and overcome ICI resistance. Patients with metastatic ICI-resistant melanoma and elevated sPD-L1 received radiotherapy to a minority of metastatic lesions, TPE, and ICI re-challenge.

Jan 14, 2025 | onlinelibrary.wiley.com | Olivia Iverson |Theresa N. Kinard |Jeffrey Winters |Lance Williams |lANCE Williams

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Jan 7, 2025 | philonomist.com | Jeffrey Winters

Elon Musk, Jeff Bezos, Bill Gates: these super-rich men influencing the governments in the US and Europe can be considered today’s oligarchs. But they don’t have to be a threat to democracy: historically, oligarchy has even helped shape modern democracies. So how can we make sure these hyper-wealthy don’t monopolise power? Jeffrey Winters, a political theorist who has closely studied these oligarchs, sheds some light on the topic. Interview by Apolline Guillot.

Aug 15, 2023 | powermotiontech.com | Sara Jensen |Jeffrey Winters

The fluid power industry and its customer markets continued to see positive economic activity in the second quarter of 2023. While the rate of growth has slowed compared to the strong demand experienced the past 2 years, there has still been growth in many segments. Second quarter financial reports from the fluid power industry, as well as its various customer markets, show manufacturers are still experiencing strong demand for their products.

Aug 14, 2023 | powermotiontech.com | Jeffrey Winters |Sara Jensen

At a Glance: ASME is taking a role in promoting small modular reactors and hydrogen fuel. Additive manufacturing may have future applications in pressure technology. Engineers also need to pay attention to AI and the mechanical properties of tissues. It isn’t just scientists who are developing tomorrow’s technology. Engineers, especially mechanical engineers, are tasked with taking clever ideas out of the research labs and making them work.