Jennie Louise

Jun 26, 2023 | onlinelibrary.wiley.com | Lisa N Yelland |Jennie Louise |Brennan C. Kahan |Tim Morris

1 INTRODUCTION Stratified randomisation is a popular approach for randomly assigning participants to treatment groups in clinical trials.1-3 It is a member of a broader class of covariate-adaptive randomisation procedures2 that take baseline covariates into account when allocating participants to treatment groups, thus preventing imbalance between the randomised groups on the chosen covariates at the trial design stage.4 To implement stratified randomisation, participants are divided into...