Jerry L. Cabriales

Nov 8, 2024 | biorxiv.org | Yohan Lee |Feng Yuan |Jeanne C. Stachowiak |Jerry L. Cabriales

AbstractTimely and precise assembly of protein complexes on membrane surfaces is essential to the physiology of living cells. Recently, protein phase separation has been observed at cellular membranes, suggesting it may play a role in the assembly of protein complexes. Inspired by these findings, we observed that protein condensates on one side of a planar suspended membrane spontaneously colocalized with those on the opposite side.