Jiamin Guo

Nov 7, 2024 | mdpi.com | Mengyue Liu |Shuang Feng |Jiamin Guo |Jia Yu

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Apr 20, 2024 | nature.com | Jiamin Guo |Li Du |Rui Su |Zhenhua Chen |Guido Marcucci |Lili Wang | +3 more

AbstractTargeting the metabolic dependencies of acute myeloid leukemia (AML) cells is a promising therapeutical strategy. In particular, the cysteine and methionine metabolism pathway (C/M) is significantly altered in AML cells compared to healthy blood cells. Moreover, methionine has been identified as one of the dominant amino acid dependencies of AML cells.