Jianping Tong

Dec 2, 2024 | mdpi.com | Bing Xu |Jie Zhang |Jianping Tong |Yi Liu

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Dec 8, 2023 | nature.com | Jianping Tong

AbstractAmacrine cells (ACs) are the most structurally and functionally diverse neuron type in the retina. Different ACs have distinct functions, such as neuropeptide secretion and inhibitory connection. Vasoactive intestinal peptide (VIP) -ergic -ACs are retina gamma-aminobutyric acid (GABA) -ergic -ACs that were discovered long ago. They secrete VIP and form connections with bipolar cells (BCs), other ACs, and retinal ganglion cells (RGCs).

Nov 16, 2023 | nature.com | Jianping Tong

AbstractIn the early stages of diabetic retinopathy (DR), diabetes-related hyperglycemia directly inhibits the AKT signaling pathway by increasing oxidative stress or inhibiting growth factor expression, which leads to retinal cell apoptosis, nerve proliferation and fundus microvascular disease.