Jiaqi Gan

Jan 11, 2025 | biorxiv.org | Yuhao Chen |Yan Zhang |Jiaqi Gan |Ke Ni

AbstractRNA velocities and generalizations emerge as powerful approaches for extracting time-resolved information from high-throughput snapshot single-cell data. Yet, several inherent limitations restrict applying the approaches to genes not suitable for RNA velocity inference due to complex transcriptional dynamics, low expression, or lacking splicing dynamics, or data of non-transcriptomic modality.

Dec 7, 2024 | biorxiv.org | Yuhao Chen |Yan Zhang |Jiaqi Gan |Ke Ni

AbstractRNA velocities and generalizations emerge as powerful approaches for exacting dynamical information from high-throughput snapshot single-cell data. Several inherent limitations restrict applying the approaches to genes not suitable for RNA velocity inference due to complex transcriptional dynamics, low expression, or lacking splicing dynamics, and data of non-transcriptomic modality.