Jiaqing Xu

Jan 13, 2025 | mdpi.com | ’s Keywords |Yaohong Wang |Jiaqing Xu |Nasrullah Dharejo

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Oct 11, 2023 | chemistry-europe.onlinelibrary.wiley.com | Xi Chen |Min Liu |Jiaqing Xu |Lei Wang

A phosphine-catalyzed (3+2) annulation of Morita-Baylis-Hillman carbonates with pyrazolinone-derived ketimines has been achieved to give various spirodihydropyrrole-dihydropyrazolones in moderate to high yields with good diastereoselectivities. The reaction tolerated diverse MBH carbonates and ketimines. Both scale-up reaction and further transformation of the product were successfully performed.

Oct 11, 2023 | chemistry-europe.onlinelibrary.wiley.com | Xi Chen |Min Liu |Jiaqing Xu |Lei Wang

A phosphine-catalyzed (3+2) annulation of Morita-Baylis-Hillman carbonates with pyrazolinone-derived ketimines has been achieved to give various spirodihydropyrrole-dihydropyrazolones in moderate to high yields with good diastereoselectivities. The reaction tolerated diverse MBH carbonates and ketimines. Both scale-up reaction and further transformation of the product were successfully performed.

Mar 1, 2023 | dx.doi.org | Yunxia Li |Ying Liu |Jiaqing Xu |Dandan Chen

Fabrication of ingenious nanomedicines to penetrate the blood–brain barrier (BBB) and blood–brain–tumor barrier (BBTB) for efficient glioblastoma (GBM) therapy remains a big challenge. In this work, macrophage–cancer hybrid membrane-camouflaged nanoplatforms were fabricated for target gene silencing-enhanced sonodynamic therapy (SDT) of GBM.