Jitao Zhang

Jul 10, 2024 | nature.com | Sainitin Donakonda |Jitao Zhang |Hannah Wintersteller |Martin Feuerherd |Juliane Siebourg-Polster |Carolin Mogler | +24 more

AbstractChronic hepatitis B virus (HBV) infection affects 300 million patients worldwide1,2, in whom virus-specific CD8 T cells by still ill-defined mechanisms lose their function and cannot eliminate HBV-infected hepatocytes3,4,5,6,7. Here we demonstrate that a liver immune rheostat renders virus-specific CD8 T cells refractory to activation and leads to their loss of effector functions.

Apr 17, 2024 | nature.com | Jitao Zhang

Giulia Ferraina and Jannick Lippuner, both 19, are my latest apprentices in the pharmaceutical research unit of F. Hoffmann-La Roche, a global company, at its headquarters in Basel, Switzerland. Both are in their fourth and final year of vocational education and training (VET), specializing in informatics and communication technology. Coaching them, just like discovering drugs, is a rewarding part of my job as a research scientist.