Jiyeon Baek

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Dysregulation of neuropilin-2 expression in inhibitory neurons impairs hippocampal circuit development and enhances risk for autism-related behaviors and seizures | Molecular Psychiatry

Nov 21, 2024 | nature.com | Deepak N Subramanian |Carol Eisenberg |Andrew Huang |Jiyeon Baek |Michael W. Shiflett |Tracy Tran

AbstractDysregulation of development, migration, and function of interneurons, collectively termed interneuronopathies, have been proposed as a shared mechanism for autism spectrum disorders (ASDs) and childhood epilepsy. Neuropilin-2 (Nrp2), a candidate ASD gene, is a critical regulator of interneuron migration from the median ganglionic eminence (MGE) to the pallium, including the hippocampus.
Dysregulation of Neuropilin-2 Expression in Inhibitory Neurons Impairs Hippocampal Circuit Development Leading to Autism-Epilepsy Phenotype

Feb 6, 2024 | biorxiv.org | Deepak N Subramanian |Carol Eisenberg |Andrew 'bunnie' Huang |Jiyeon Baek

AbstractDysregulation of development, migration, and function of interneurons, collectively termed interneuronopathies, have been proposed as a shared mechanism for autism spectrum disorders (ASDs) and childhood epilepsy. Neuropilin-2 (Nrp2), a candidate ASD gene, is a critical regulator of interneuron migration from the median ganglionic eminence (MGE) to the pallium, including the hippocampus.

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