Joachim W Fluhr

Aug 7, 2024 | onlinelibrary.wiley.com | Joachim W Fluhr |Pharmacology ITMP |Peter Menzel |Rolf Schwarzer

INTRODUCTION The barrier protective function predominantly resides in the stratum corneum (SC) of the epidermis and accomplishes an effective barrier towards the uncontrolled loss of water and the penetration of potentially harmful exogenous substances through the skin [1-3]. The SC, the outermost layer of the epidermis, comprises a lipid matrix primarily composed of ceramides, cholesterol and free fatty acids [1, 4-6].

Jul 28, 2024 | onlinelibrary.wiley.com | Joachim W Fluhr |Andrew Alexis |Anneke Andriessen |Peter Nissen Bjerring

Introduction In the literature, the term senile xerosis has been used for aging populations that show symptoms of xerosis. However, the etiology of xerosis and age of occurrence lack definition. The panel proposes the term mature xerosis be used for subjects over 50 who suffer from age-related xerosis and replace senile xerosis to describe the phenomenon.