Joel Z. Nordin
Articles
T cell toxicity induced by tigecycline binding to the mitochondrial ribosome - Nature Communications
1 month ago |
nature.com | Anas Khawaja |Minh Duc Nguyen |Minh Nguyễn |Vivek Singh |Yong Liu |Joel Z. Nordin | +2 more
AbstractTetracyclines are essential bacterial protein synthesis inhibitors under continual development to combat antibiotic resistance yet suffer from unwanted side effects. Mitoribosomes - responsible for generating oxidative phosphorylation (OXPHOS) subunits - share structural similarities with bacterial machinery and may suffer from cross-reactivity.
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