Articles
T cell toxicity induced by tigecycline binding to the mitochondrial ribosome - Nature Communications
1 month ago |
nature.com | Anas Khawaja |Minh Duc Nguyen |Minh Nguyễn |Vivek Singh |Yong Liu |Joel Z. Nordin | +2 more
AbstractTetracyclines are essential bacterial protein synthesis inhibitors under continual development to combat antibiotic resistance yet suffer from unwanted side effects. Mitoribosomes - responsible for generating oxidative phosphorylation (OXPHOS) subunits - share structural similarities with bacterial machinery and may suffer from cross-reactivity.
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May 19, 2024 |
onlinelibrary.wiley.com | Minh Duc Nguyen |Minh Nguyễn |Darby IB
DATA AVAILABILITY STATEMENT The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.
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