John D. Minna

Nov 11, 2024 | cell.com | Jinli Wang |Nikole L. Fendler |Ashutosh Shukla |Shwu-Yuan Wu |Ashwini Challa |Jeon Lee | +5 more

KeywordsRNA polymerase IItranscriptionPAF1ARFp53tumor suppressorRUNXcell proliferationtumorigenesisCDKN2AGet full text accessLog in, subscribe or purchase for full access. References1. Pope, S.D. ∙ Medzhitov, R. Emerging principles of gene expression programs and their regulationMol. Cell. 2018; 71:389-3972. Cramer, P. Organization and regulation of gene transcriptionNature. 2019; 573:45-543. Statello, L. ∙ Guo, C.J. ∙ Chen, L.L. ... Gene regulation by long non-coding RNAs and its biological functionsNat.

Jan 19, 2024 | science.org | Chiho Kim |Xu-Dong Wang |Zhengshuai Liu |Jianwei Hao |Shuai Wang |Peng Li | +11 more

Dec 10, 2023 | nature.com | Shidan Wang |Qin Zhou |Xinyi Zhang |Zhikai Chi |Siyuan Zhang |John D. Minna

AbstractRecent advancements in tissue imaging techniques have facilitated the visualization and identification of various cell types within physiological and pathological contexts. Despite the emergence of cell-cell interaction studies, there is a lack of methods for evaluating individual spatial interactions. In this study, we introduce Ceograph, a cell spatial organization-based graph convolutional network designed to analyze cell spatial organization (for example,.