Shidan Wang

Oct 9, 2024 | digitalcommons.library.tmc.edu | Xinyi Zhang |Frederico O. Gleber-Netto |Shidan Wang |Kevin Jin

AbstractHead and neck squamous cell carcinoma (HNSCC), specifically in the oral cavity (oral squamous cell carcinoma, OSCC), is a common, complex cancer that significantly affects patients' quality of life. Early diagnosis typically improves prognoses yet relies on pathologist examination of histology images that exhibit high inter- and intra-observer variation. The advent of deep learning has automated this analysis, notably with object segmentation.

Dec 10, 2023 | nature.com | Shidan Wang |Qin Zhou |Xinyi Zhang |Zhikai Chi |Siyuan Zhang |John D. Minna

AbstractRecent advancements in tissue imaging techniques have facilitated the visualization and identification of various cell types within physiological and pathological contexts. Despite the emergence of cell-cell interaction studies, there is a lack of methods for evaluating individual spatial interactions. In this study, we introduce Ceograph, a cell spatial organization-based graph convolutional network designed to analyze cell spatial organization (for example,.

Nov 4, 2023 | biorxiv.org | Shidan Wang |Yiqing Wang |Ruichen Rong |Andrew Koh

AbstractRecent technological advances have highlighted the significant impact of the human microbiome and metabolites on physiological conditions. Integrating microbiome and metabolite data has shown promise in predictive capabilities. We developed a new supervised contrastive learning framework, MB-SupCon-cont, that (1) proposes a general contrastive learning framework for continuous outcomes and (2) improves prediction accuracy over models using single omics data.

Jul 31, 2023 | mdpi.com | Xinyi Zhang |Frederico O. Gleber-Netto |Shidan Wang |Kevin Jin

Open AccessArticlebyXinyi Zhang 1,†, Frederico O. Gleber-Netto 2,†, Shidan Wang 1, Kevin W. Jin 1, Donghan M. Yang 1, Ann M. Gillenwater 2, Jeffrey N. Myers 2, Renata Ferrarotto 3, Curtis R.