Articles

  • 1 week ago | fredhutch.org | John Higgins

    Small cell lung cancer, or SCLC, is aggressive, lethal and particularly cruel because chemotherapy initially works so well. But within just a few months, SCLC becomes resistant to drugs and dashes hopes. “What is seen in the clinic is often quite remarkable responses to chemotherapy initially, but these are just transient responses and tumors come back,” said David MacPherson, PhD, a Fred Hutch Cancer Center scientist who specializes in small cell lung cancer.

  • 3 weeks ago | fredhutch.org | John Higgins

    From the earliest days of the pandemic that shocked the world in 2020, researchers at Fred Hutch Cancer Center tracked the rapid evolution and spread of the virus that causes COVID-19 by studying how its genomic sequence — the order of its genetic building blocks — changed over time.

  • 4 weeks ago | fredhutch.org | John Higgins

    Some things just go together like “rock and roll” and “fish and chips” or, in molecular biology, “transcription factors” and the “nearby genes they regulate.” The standard, simplified story goes like this: transcription factors are molecular workers that scan DNA strands and bind to specific sequences close to the genes they either turn on or off.

  • 1 month ago | digitaltrends.com | John Higgins

    Table of Contents If there’s one thing that you can say about Samsung, it’s that they are doggedly dedicated — some might say stubborn — but however you want to spin it, it’s clear that Samsung has a vision and will see it through, come hell or high water. Not going to lie, I respect that. But what does all that have to do with Samsung’s best Neo QLED mini-LED TVs? It’s all about their 8K TV strategy.

  • 1 month ago | fredhutch.org | John Higgins

    After 40 years at Fred Hutch Cancer Center asking good questions of his own science and the science of his colleagues, cell biologist Jonathan Cooper, PhD has retired from the Basic Sciences Division. He made his name in biology by identifying key components of a complex relay system that enables cells to communicate with each other.

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John Higgins
John Higgins @jhigginsST
23 Apr 25

RT @science_seattle: 🧬 Surprising findings from the Hahn Lab at @fredhutch! Dr. @LMahendrawada’s new study shows yeast transcription facto…

John Higgins
John Higgins @jhigginsST
16 Apr 25

Honored to work with and write about such smart people 🤓 !

Lakshmi Mahendrawada
Lakshmi Mahendrawada @LMahendrawada

Honored to see our work highlighted by @fredhutch and @HutchBasicSci. In this study, We mapped the binding and regulatory targets of nearly all yeast transcription factors and found that the classic model often doesn’t hold. Check out the paper here https://t.co/BYqmrv72M2

John Higgins
John Higgins @jhigginsST
16 Apr 25

RT @LMahendrawada: Honored to see our work highlighted by @fredhutch and @HutchBasicSci. In this study, We mapped the binding and regulator…