Fred Hutch News Service

At Fred Hutch, our diverse teams of leading scientists and dedicated humanitarians collaborate to tackle cancer, HIV/AIDS, and other health challenges. Among our researchers are three Nobel Prize winners, all driven by an unwavering commitment to advancing health knowledge and spreading hope globally. Our collective efforts focus on finding innovative methods for early cancer detection, when treatment success is greatest; creating effective therapies with reduced side effects; and exploring strategies to prevent cancer development altogether.

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Rewriting the story about the molecules that turn genes on and off

1 week ago | fredhutch.org | John Higgins

Some things just go together like “rock and roll” and “fish and chips” or, in molecular biology, “transcription factors” and the “nearby genes they regulate.” The standard, simplified story goes like this: transcription factors are molecular workers that scan DNA strands and bind to specific sequences close to the genes they either turn on or off.
Multiple myeloma is treatable, not curable. Is that set to change?

3 weeks ago | fredhutch.org | Bonnie Rochman

At age 89, Cal Crow plays water volleyball three days a week, then chases that with a 1,000-foot swim; on his off days, he logs at least a mile around his neighborhood — and that’s with a cancer diagnosis. In 2019, Crow was having trouble hearing and went to see a physician who misdiagnosed him. He sought a second opinion at Fred Hutch Cancer Center, where a full body scan revealed that Crow had multiple myeloma. “I didn’t know what that was,” said Crow.
Cell biologist and former Fred Hutch division leader Dr. Jonathan Cooper retires

4 weeks ago | fredhutch.org | John Higgins

After 40 years at Fred Hutch Cancer Center asking good questions of his own science and the science of his colleagues, cell biologist Jonathan Cooper, PhD has retired from the Basic Sciences Division. He made his name in biology by identifying key components of a complex relay system that enables cells to communicate with each other.
Physician assistant cares for colon cancer patients - then she became one

1 month ago | fredhutch.org | Bonnie Rochman

FacebookLinkedInTwitterEmail The diagnosis came out of nowhere for 38-year-old Bekah Kooy was convinced she had food poisoning when she felt nauseated and experienced stomach pain following lunch one day in February 2023. By the next day, the pain had moved to the right side of her abdomen and she wondered if her gall bladder might be the culprit.
Drs. Keith Jerome and Jesse Bloom elected fellows of American Academy of Microbiology

1 month ago | fredhutch.org | Sabrina Richards

Jerome’s lab, in the Vaccine and Infectious Disease Division at Fred Hutch, focuses on viruses that persist in their hosts and evade the immune system. While viruses like influenza come and go, others can set up permanent homes in our cells. Viruses like herpes simplex virus (HSV), hepatitis B, HIV and (occasionally) human papillomavirus, have found different ways to stick with us.
With respiratory infections rampant, experts urge masking and vaccination

1 month ago | fredhutch.org | Bonnie Rochman

During one of the most active flu seasons in recent memory, infectious disease experts at Fred Hutch Cancer Center say many of the public health lessons learned during the COVID-19 epidemic still apply: wear well-fitting masks in crowded indoor poorly ventilated spaces, practice good hand hygiene and get vaccinated. There are three vaccines available to protect against respiratory viruses: flu, COVID-19 and RSV. And no, it’s not too late to get vaccinated this season.
Fred Hutch deploys AI technology to help analyze colonoscopies

1 month ago | fredhutch.org | Bonnie Rochman

Endoscopists who perform colonoscopies are trained to zoom in on the nooks and crannies of the colon, the glossy pink five-foot-long tunnel that snakes through the abdomen. They are on the prowl for polyps, small clumps of cells that may turn cancerous if not removed. "Some polyps are quite large and we would never miss those," said David Hockenbery, MD, medical director of the procedure suite and head of gastroenterology and hepatology at Fred Hutch Cancer Center.
New methods reveal cancer mechanism in ancient genes

1 month ago | fredhutch.org | John Higgins

Researchers at Fred Hutch Cancer Center have discovered an overlooked mechanism driving aggressive breast and brain tumors involving genes so ancient — more than 2 billion years old — that they fly under the radar of standard genetic sequencing methods. “Identifying this mechanism suggests it could be a new test to diagnose cancers and possibly treat them,” said Fred Hutch molecular biologist Steven Henikoff, PhD, co-first author of a study recently published in the journal Science.
Evolutionary cell biologist Dr. Grant King named a Hanna Gray Fellow

2 months ago | fredhutch.org | John Higgins

The pursuit of knowledge runs deep in King’s family: His parents, two of his grandparents, and even one great-grandparent all received PhDs.They indulged his curiosity about life, taking him to the Santa Barbara Zoo nearly every weekend and allowed him to keep pond scum in a closet for weeks to see what would emerge from the slime. He was just as fascinated by the diversity of life he could not see — the world of microbes.
Cold air makes oxygen toxic for worms

Jan 22, 2025 | fredhutch.org | John Higgins

Most people who try to hitch a free flight hiding in a jet’s wheel-well die in the attempt, like the person whose body was discovered on Christmas Eve after a flight from Chicago landed on Maui. But occasionally someone survives the extreme cold and oxygen deprivation of flying several hours at a high altitude outside the plane’s pressurized and warmed passenger cabin.