John Mandrola

2 days ago | sensible-med.com | Adam Cifu |Vinay Prasad |John Mandrola

In the coming weeks Vinay, John, and I (Adam) will be getting together in person. We are meeting to work on what we think will be some really valuable Sensible Medicine content. Since we will have some time together, we thought it would be a good time to gather some more questions to answer. Same rules as last time: the comments are open to all paid subscribers to pose questions. Ask anything and we promise to take a swing at any and all questions. Photo Credit: Ilkka Kärkkäinen

4 days ago | sensible-med.com | Adam Cifu |Vinay Prasad |John Mandrola

It is hard to believe that we are coming up to the third anniversary of Sensible Medicine, well into toddlerhood. None us could have predicted that the site would last this long or be this successful (93,000 subscribers!!!!). The three of us are getting ready to meet up in person for the first time and we thrilled to see what the future will bring. We have some exciting plans. Three years seems a reasonable milestone to call for some reflection.

1 week ago | sensible-med.com | John Mandrola

Not every week, but most weeks I read social media posts about getting your heart checked. It could be lifesaving. The pleas often start with a coronary artery calcium scan—which could then lead to a coronary angiogram with possible stent placement. It’s a compelling story. Heart disease is a leading killer. Sudden cardiac death or massive heart attack can be the first symptom. So if you find a widow-maker-type blockage, you can have it fixed, and disaster is averted.

1 week ago | medscape.com | John Mandrola

Please note that the text below is not a full transcript and has not been copyedited. For more insight and commentary on these stories, subscribe to the This Week in Cardiology podcast, download the Medscape app or subscribe on Apple Podcasts, Spotify, or your preferred podcast provider. This podcast is intended for healthcare professionals only. For the week ending April 11, 2025, John Mandrola, MD, comments on the following topics: The TAP-IT, STRIDE, FreshUP, and SINGLE SHOT CHAMPION trials.

2 weeks ago | sensible-med.com | John Mandrola

Patients who present with acute fluid accumulation and congestion due to heart failure often develop something called a pleural effusion. The fluid is not in the lung, but around the lung. It compresses the lung, creating shortness of breath, chest pressure, and other symptoms. We call such a fluid accumulation extra-vascular because it is not inside the blood vessels. Rather, it is in a separate space outside of the lungs.