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1 month ago | 
hcplive.com | John S. Barbieri |Patrick Campbell
The risk of benzene in products containing benzoyl peroxide was a hot topic of discussion in dermatology for 2024, primarily as the result of a report from independent testing company Valisure suggesting the known human carcinogen could form at high levels in many common acne products.1 According to the March 2024 report from Valisure, tests indicated on-market benzoyl peroxide products can form over 800 times the conditionally restricted FDA concentration limit of 2 parts per million for...
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2 months ago | 00113-7/fulltext&sz=64)
jidonline.org | John S. Barbieri |Courtney Rubin |James Pham |Michelle Wong
Keywordsbenzenebenzoyl peroxidesafetyriskcancerWe read with interest the article by Kucera et al. (Kucera et al. 20248. Kucera, K. ∙ Zenzola, N. ∙ Hudspeth, A. ... Evaluation of Benzene Presence and Formation in Benzoyl Peroxide Drug ProductsJ. Invest. Dermatol. 2024;) and agree that this topic is of tremendous importance given the ubiquitous use of benzoyl peroxide (BPO) for acne and other skin conditions.
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2 months ago | 
jamanetwork.com | John S. Barbieri |Courtney Rubin |James Pham |Michelle Wong
The Role of Formulation in Benzene Formation in Benzoyl Peroxide Products Podcast (19:14) 0:00 / 0:00 Although benzoyl peroxide is a foundational acne treatment without a clear alternative,1 there have been concerns about the potential for benzoyl peroxide to break down into benzene, a known human carcinogen.2 Although this issue may not pose a clinically meaningful risk,3-5 it is still important to identify strategies to minimize benzene formation in benzoyl peroxide–containing products....
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Jan 17, 2025 | 
healio.com | Rebecca Forand |Kristen Dowd |John S. Barbieri
You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Key takeaways: Higher cumulative doses of isotretinoin showed a decreased risk for acne relapse. These findings suggest an individualized approach to care should be implemented.
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Nov 22, 2024 | 
healio.com | Rebecca Forand |Kristen Dowd |John S. Barbieri
You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Key takeaways: Male and female patients with acne often present and have different skin physiology. Patients treated with triple combination CAB gel experienced similar efficacy and safety, regardless of sex.
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Oct 9, 2024 | 
healio.com | Gabrielle Capaldo |Kristen Dowd |John S. Barbieri
You've successfully added Acne to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Key takeaways: A total of 111 benzoyl peroxide products stored at room temperature were substantially contaminated with benzene. 38 of the 111 products contained benzene concentrations that exceeded the FDA’s limit.
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Sep 18, 2024 | 
onlinelibrary.wiley.com | John S. Barbieri |Dora Farkas |Aarhus Denmark |Niels Skipper
CONFLICT OF INTEREST STATEMENT John S Barbieri has received consulting fees from Dexcel Pharma for work unrelated to the present study. Sigrun AJ Schmidt has received speaker honoraria from GSK Pharma for lectures unrelated to the present study. Line Kibsgaard has received consulting fees as a speaker from Astra Seneca A/S, Leo-Pharma and Novartis.
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Jul 17, 2024 | 
dermatologytimes.com | Maddi Hebebrand |John S. Barbieri
John Barbieri, MD, MBA, FAAD, recently spoke with Dermatology Times on his research into benzoyl peroxide containing products and benzene. Barbieri’s dual studies found no increased cancer risk for patients utilizing benzoyl peroxide products. Transcript:John Barbieri: Hi, I'm Dr John Barbieri. I'm a board-certified dermatologist at the Brigham and Women's Hospital and Harvard Medical School in Boston, Massachusetts.
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Jun 14, 2024 | 
healio.com | Rebecca Forand |Kristen Dowd |John S. Barbieri
Read more You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Key takeaways: In patients receiving masculinizing gender-affirming care, isotretinoin was successful in improving acne.
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May 20, 2024 | 
healio.com | Gabrielle Capaldo |Kristen Dowd |John S. Barbieri
You've successfully added to your alerts. You will receive an email when new content is published. Click Here to Manage Email Alerts We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Key takeaways: Those taking isotretinoin exhibited a 7.85 times increased risk for severe hypertriglyceridemia vs. those taking oral antibiotics. They were also 1.45 times more likely to have severely elevated liver enzymes.
