John Wade

1 month ago | cell.com | Joshua J. Hamey |Manan Shah |John Wade |Tara K. Bartolec |Kate Quinlan |Nicholas Williamson | +2 more

Keywordsribosometranslationlysine methylationmethyltransferasesubstrate specificityResearch topic(s)CP: Molecular biologyIntroductionFor over half a century, it has been known that the eukaryotic protein translational machinery is highly modified by protein methylation.1 Only in the last two decades, however, have enzymes catalyzing the methylation of ribosomes and translation factors been discovered.