Nicholas Williamson

1 month ago | cell.com | Joshua J. Hamey |Manan Shah |John Wade |Tara K. Bartolec |Kate Quinlan |Nicholas Williamson | +2 more

Keywordsribosometranslationlysine methylationmethyltransferasesubstrate specificityResearch topic(s)CP: Molecular biologyIntroductionFor over half a century, it has been known that the eukaryotic protein translational machinery is highly modified by protein methylation.1 Only in the last two decades, however, have enzymes catalyzing the methylation of ribosomes and translation factors been discovered.

Dec 11, 2024 | cell.com | Marziyeh Anari |Hamzeh Karimkhanloo |Shuai Nie |Li Dong |Gio Fidelito |Jacqueline A. Bayliss | +11 more

Keywords lipoprotein lipase very low-density lipoprotein tissue communication ceramide phospholipid lipid metabolism Research topic(s) CP: Metabolism Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD) is defined as steatotic liver disease in the presence of one or more cardiometabolic risk factors, including obesity, type 2 diabetes, and dyslipidemia.1 Metabolic dysfunction-associated steatohepatitis (MASH) is the more severe form of MASLD, and in addition to excess...