John Warrington

Nov 16, 2024 | miltonkeynes.co.uk | John Warrington

Watch more of our videos on ShotsTV.com and on Freeview 262 or Freely 565Visit Shots! nowThe country pub, as an institution, is under threat as never before. Pubs across England and Wales are being closed at a rate of two a day, most of them never to reopen. Former landlord of the Globe Inn at Hanslope has novelised the experience and challenges of running a country pub in the 21st Century.

Nov 8, 2023 | nature.com | Quinlen Marshall |John Warrington |Alvin Farrel |David Groff |Sarvind Tripathi |Son Nguyen | +3 more

AbstractThe majority of oncogenic drivers are intracellular proteins, constraining their immunotherapeutic targeting to mutated peptides (neoantigens) presented by individual human leukocyte antigen (HLA) allotypes1. However, most cancers have a modest mutational burden that is insufficient for generating responses using neoantigen-based therapies2,3. Neuroblastoma is a paediatric cancer that harbours few mutations and is instead driven by epigenetically deregulated transcriptional networks4.