Jonathan Thevenet

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A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy - Nature Biotechnology

Oct 11, 2024 | nature.com | Florian Huber |Marion Arnaud |Fabrizio Benedetti |Jonathan Thevenet |Johanna Chiffelle |Markus K Muller | +7 more

AbstractThe accurate identification and prioritization of antigenic peptides is crucial for the development of personalized cancer immunotherapies. Publicly available pipelines to predict clinical neoantigens do not allow direct integration of mass spectrometry immunopeptidomics data, which can uncover antigenic peptides derived from various canonical and noncanonical sources.
A comprehensive proteogenomic pipeline for neoantigen discovery to advance personalized cancer immunotherapy - Nature Biotechnology

Oct 11, 2024 | nature.com | Florian Huber |Marion Arnaud |Fabrizio Benedetti |Jonathan Thevenet |Johanna Chiffelle |Markus K Muller | +7 more

AbstractThe accurate identification and prioritization of antigenic peptides is crucial for the development of personalized cancer immunotherapies. Publicly available pipelines to predict clinical neoantigens do not allow direct integration of mass spectrometry immunopeptidomics data, which can uncover antigenic peptides derived from various canonical and noncanonical sources.

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