Joost M. Riphagen

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Ultra-high field imaging, plasma markers and autopsy data uncover a specific rostral locus coeruleus vulnerability to hyperphosphorylated tau - Molecular Psychiatry

Apr 5, 2023 | nature.com | Hyun-Sik Yang |Kaj Blennow |Oskar Hansson |Henrik Zetterberg |Maxime Van Egroo |Joost M. Riphagen

AbstractAutopsy data indicate that the locus coeruleus (LC) is one of the first sites in the brain to accumulate hyperphosphorylated tau pathology, with the rostral part possibly being more vulnerable in the earlier stages of the disease.

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